NFL Week 2 picks, predictions, schedule, odds, fantasy tips

Week 2 of the 2026 NFL season is right here! There are a number of powerful division matchups taking place: the Vikings visiting the Bears, the Panthers and Falcons going through off, the Raiders in opposition to the Chargers and the Seahawks versus the Cardinals. You may also count on an thrilling quarterback duel between Jacksonville’s Trevor Lawrence and Denver’s Bo Nix.

We’re right here to get you prepared for the motion. First, our NFL Nation reporters take you contained in the locker room with the perfect factor they heard this week, and ESPN Research offers a key stat to know. Then, analytics author Seth Walder makes a daring prediction for every matchup, NFL analyst Ben Solak offers one motive to tune in to every sport (and charges the watchability of the matchup), fantasy analyst Eric Moody shares fantasy football intel and betting analyst Pamela Maldonado hits betting insights for every contest. We even have Football Power Index (FPI) sport projections, and Maldonado, Moody and Walder give us closing rating picks for each sport.

Let’s get into the total Week 2 slate, which culminates with a “Monday Night Football” matchup between the Giants and Rams on ESPN. (Game occasions are Sunday except in any other case famous, and all odds are through DraftKings.)

Jump to a matchup:
MIN-CHI | CIN-HOU | NO-BAL
PIT-NE | GB-NYJ | PHI-TEN
CAR-ATL | CLE-TB | JAX-DEN
LV-LAC | WSH-DAL | SEA-ARI
MIA-SF | IND-KC | NYG-LAR

What ESPN Analytics says …

1 p.m. ET | Fox | CHI -4.5 (47.5 O/U)

What we’re listening to on the Vikings: DC Brian Flores posted an 83% blitz fee within the first half in opposition to the Packers and — even after throttling down within the second half — completed with a 71.7% fee that just about tripled the NFL common in Week 1. Flores has all the time favored the blitz, however would he dare repeat that aggression stage in opposition to the Bears? Flores considers the opening weeks of a season to be about enchancment and experimentation. “What are the best groups of players who are out on the field? Who plays well with who?” he mentioned. “That’s what we’re working through as a staff right now.” — Kevin Seifert

What we’re listening to on the Bears: Chicago is making ready for the “King of the Cover 0 blitz,” the nickname QB Caleb Williams gave Flores as a rookie. In 2025, Williams was blitzed 37.2% in his first assembly in opposition to Minnesota and 66.7% the second time. Trying to anticipate which technique Flores will deploy is an ineffective plan. “You try to have answers for everything,” coach Ben Johnson mentioned. “He’s been in this division three years now, and yeah, I mean you’d like to think he’s put everything he could possibly do on tape until you play him next and you realize he hasn’t yet. … There always is with him and that’s what makes him such a good coordinator.” — Courtney Cronin

Stat to know: The Bears want 37 factors to interrupt the NFL report for many factors in a group’s opening two video games, at the moment held by the 1968 Raiders (95). — ESPN Research

Bold prediction: Vikings QB Carson Wentz will throw a number of interceptions. I do know he had some spectacular moments and did not throw any picks in Minnesota’s Week 1 win. But that is nonetheless Wentz, and I assume he is nonetheless vulnerable to a mistake or 4. — Walder

Viewers ranking (out of 10): 9.0. There is not a extra enjoyable schematic matchup in the whole league than Johnson versus Flores. This is Round 7 of their showdown. With a nasty Bears protection on the opposite facet of the ball, there ought to be explosive performs in every single place. — Solak

Injuries: Vikings | Bears

Fantasy nugget: Bears WR Luther Burden III completed with simply 5 targets and 9.5 fantasy factors in opposition to Carolina final week. However, he led Chicago’s receivers in routes run and now faces a Vikings secondary that allowed the Packers’ Christian Watson and Matthew Golden to mix for 48.2 fantasy factors final week. Burden is in a great spot to bounce again. See Week 2 rankings. — Moody

Betting perception: All 5 of Wentz’s begins went over the whole final season for the Vikings. Chicago simply scored 59 factors but additionally allowed Carolina to provide 478 yards and 37 factors. Minnesota’s protection now faces an explosive Bears offense, whereas Wentz and WR Justin Jefferson get a susceptible Chicago protection. Read more. — Maldonado

Maldonado’s choose: Bears 31, Vikings 24
Moody’s choose: Bears 35, Vikings 26
Walder’s choose: Bears 34, Vikings 17
FPI prediction: CHI, 65.6% (by a median of 4.5 factors)

Matchup must-reads: Mason put on IR after having surgery on thumb … Bears anticipate ‘great challenge’ vs. Vikings defense … No block, no rock’ is not just a mantra for Bears’ offense

1 p.m. ET | CBS | HOU -2.5 (46.5 O/U)

What we’re listening to on the Bengals: QB Joe Burrow will probably be managing back tightness this week. And he’ll be doing so in opposition to one of many NFL’s greatest defenses. OC Dan Pitcher in contrast the mixture of edge rushers Danielle Hunter and Will Anderson Jr. to Cincinnati’s WR tandem of Ja’Marr Chase and Tee Higgins. Keeping Burrow upright and intact this week will probably be paramount for Cincinnati’s probabilities in opposition to Houston and for the remainder of the season. — Ben Baby

What we’re listening to on the Texans: Houston is looking at one other potential 0-2 begin. If the Texans lose this week, it will be the third such time below coach DeMeco Ryans since he was employed in 2023. But Hunter mentioned “last year is last year,” in response to being requested about their confidence stage to dig themselves out of a gap to begin the season. Houston could should play with out Pro Bowl wideout Nico Collins (hamstring), who was injured in follow Wednesday. — DJ Bien-Aime

Stat to know: The Bengals posted a 54% go rush win fee in Week 1, the group’s highest since November 2024. They had the worst go rush win fee within the NFL final season (28.8%). — ESPN Research

Bold prediction: Texans RB David Montgomery will common 5.0 yards per carry. Montgomery scored three touchdowns in his debut however solely averaged 3.0 yards per carry. The Bengals’ protection, for all its turnover success in Week 1, did enable .09 EPA per opponent carry in Week 1 — the fifth-worst mark. — Walder

Viewers ranking (out of 10): 8.8. There are excessive stakes on this one for the Texans, who’re making an attempt to keep away from 0-2 (in opposition to two AFC contenders!). This is one I’m going to maintain an in depth eye on particularly as a result of Burrow and Collins are coming into the week banged up. — Solak

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Compton on Burrow’s again tightness: ‘I’d be afraid’ as a Bengals fan

Injuries: Bengals | Texans

Fantasy nugget: Montgomery completed Week 1 with 23 touches and 28.9 fantasy factors, whereas dealing with each Houston speeding try contained in the pink zone. He now faces a Bengals protection that ranked twenty first in run cease win fee (25.8%) final week and allowed the Bucs’ Bucky Irving to attain 20.3 fantasy factors. See Week 2 rankings. — Moody

Betting perception: The Texans are 1-8 ATS (in opposition to the unfold) in September below Ryans for the previous three seasons, and their September struggles might proceed in opposition to an offense constructed to assault Houston’s Week 1 weak point. The Bills averaged 10.4 yards per go in opposition to the Texans, and so they now get Burrow, Chase and Higgins. If Cincinnati protects Burrow, it has sufficient offense to contend. Read more. — Maldonado

Maldonado’s choose: Bengals 27, Texans 24
Moody’s choose: Bengals 24, Texans 21
Walder’s choose: Texans 23, Bengals 20
FPI prediction: HOU, 55.9% (by a median of 1.6 factors)

Matchup must-reads: Burrow: ‘Ridiculous’ that tight back would keep me out … To’oTo’o to miss some time with shoulder injury … Cashing in: Bengals rookie Howell impacts pass rush … Could Montgomery be key to unlock offense?

1 p.m. ET | CBS | BAL -8.5 (46.5 O/U)

What we’re listening to on the Saints: The Saints will probably be with out long-snapper Zach Wood for a number of weeks due to a calf strain, in accordance with a supply. This is a really underrated loss for New Orleans, which hasn’t needed to take care of this downside for the ten seasons Wood has been with the group. Wood has been quietly constant in his time with the Saints, however now they’re going to should scramble to discover a new long-snapper with just a few days to go earlier than the sport. DT John Ridgeway III was the emergency long-snapper in coaching camp. — Katherine Terrell

What we’re listening to on the Ravens: Baltimore believes the important thing to stopping the Saints is slowing down WR Chris Olave, who had a career-high 182 yards in Week 1. Olave is trying to turn into the primary Saints participant in seven seasons to report 4 straight video games with 100 yards receiving. The Ravens, who performed zone protection 76% of the time final week, know it should take a group effort. “I think putting a cap on Olave is kind of where it starts,” CB Marlon Humphrey mentioned. “If you can kind of hold him to the lower side of receptions and yards, then you have a good chance. But Olave has kind of been the force.” — Jamison Hensley

Stat to know: The Saints performed zone protection on 38 of 40 dropbacks (95%) in Week 1, per NFL Next Gen Stats. Since the beginning of final season, quarterback Lamar Jackson is third in QBR versus man protection (83.6) and twenty third in QBR versus zone protection (44.2) amongst 28 certified QBs. — ESPN Research

Bold prediction: Ravens guard Olaivavega Ioane will report a 90% go block win fee, up from the 82% he recorded final week and above the league’s common of 87% for guards. Offensive linemen are likely to battle of their rookie season, however the Saints’ inside rushers should not be significantly threatening. — Walder

Viewers ranking (out of 10): 8.2. The Ravens’ offense was the can’t-miss blockbuster of Week 1, whereas the Saints coated a 21-point second-half deficit to pressure time beyond regulation in Detroit. Even if the Ravens get one other massive lead, this one will not be one to show off early. — Solak

Injuries: Saints | Ravens

Fantasy nugget: WR Devaughn Vele led all Saints ability place gamers in snaps and routes run final week and completed with 19.9 fantasy factors. New Orleans enters Week 2 as an enormous underdog in a sport with a excessive projected whole. The Saints could possibly be enjoying from behind once more, giving Vele one other alternative to provide. See Week 2 rankings. — Moody

Betting perception: The Saints have coated six straight video games as underdogs and 6 straight video games on the highway. New Orleans has sufficient offense to maintain this inside a landing, as QB Tyler Shough threw for 410 yards in opposition to Detroit, and Olave is a dependable receiving choice. The Ravens ought to transfer the ball with Jackson and RB Derrick Henry. Read more. — Maldonado

Maldonado’s choose: Ravens 30, Saints 23
Moody’s choose: Ravens 30, Saints 20
Walder’s choose: Ravens 28, Saints 16
FPI prediction: BAL, 76% (by a median of seven.7 factors)

Matchup must-reads: Moore optimistic Saints RB Kamara will be back for Week 2 … Ravens place promising rookie WR Lane on IR … Shough expects less jitters vs. Ravens

1 p.m. ET | CBS | NE -5.5 (41.5 O/U)

What we’re listening to on the Steelers: Pittsburgh was 3-of-13 on third down in Week 1. Four of the missed third downs got here as QB Aaron Rodgers focused WR DK Metcalf. On one play, Metcalf was flagged for go interference. On one other deep shot, it appeared the defender interfered with Metcalf, and a flag wasn’t thrown. But on at the very least a kind of third-down makes an attempt, a catchable ball bounced off Metcalf’s arms. He completed the sport with simply 4 catches for 40 yards on 10 targets, however Rodgers doubled down in his perception in Metcalf. “I’m not worried about DK at all, man,” Rodgers mentioned. “I love DK. He’s one of my closest friends on the team, and I’m going to keep feeding him.” — Brooke Pryor

What we’re listening to on the Patriots: Coach Mike Vrabel got here ready with an eye-popping stat when he met with the media to kick off the week, noting that Steelers defenders T.J. Watt and Cameron Heyward have mixed for 64 go breakups over the previous 5 seasons as go rushers. Vrabel additionally famous, “If you don’t take care of the edges, it’s going to be an issue.” So it is a main check for OTs Will Campbell and Morgan Moses and the offensive line. — Mike Reiss

Stat to know: QB Drake Maye threw a career-high three interceptions in Week 1. The Steelers have pressured a number of turnovers in 9 video games because the starting of final season, tied for third most within the NFL. — ESPN Research

Bold prediction: Metcalf will report 80-plus receiving yards. Though he managed solely 40 receiving yards in Week 1, Metcalf obtained 181 whole air yards on his targets. We ought to count on him to transform these air yards into precise yards at a better fee going ahead. — Walder

Viewers ranking (out of 10): 7.2. The Steelers bought a pleasant win in opposition to the Patriots final season by forcing Maye into tons of uncharacteristic errors within the pocket. The Patriots come into this sport in opposition to Pittsburgh determined for a win after back-to-back embarrassing losses to Seattle. High stakes! — Solak

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Can Drake Maye and the Patriots bounce again vs. the Steelers?

Injuries: Steelers | Patriots

Fantasy nugget: Patriots TE Hunter Henry managed simply 26 yards in Week 1, however A.J. Brown‘s ankle injury ought to result in extra targets. Henry ranked second on the Patriots slot snaps final week and has averaged 15.5 fantasy factors in video games for New England with at the very least six targets. See Week 2 rankings. — Moody

Betting perception: New England was 7-4 to the below at residence final season, and this development might proceed. Pittsburgh’s offense scored simply 13 factors in opposition to Atlanta. The Patriots scored solely 10 factors in Seattle, whereas their protection allowed 13. Pittsburgh can strain Maye, and New England’s protection could make Rodgers work for each yard. Read more. — Maldonado

Maldonado’s choose: Patriots 19, Steelers 17
Moody’s choose: Patriots 27, Steelers 20
Walder’s choose: Patriots 27, Steelers 17
FPI prediction: NE, 66.1% (by a median of 4.3 factors)

Matchup must-reads: Coach McCarthy noncommittal on Porter’s timeline to return … How will Patriots cope with losing Brown for four weeks? … Tracking Rodgers’ 2026 NFL season

1 p.m. ET | Fox | GB -3.5 (44.5 O/U)

What we’re listening to on the Packers: Whatever the box score from Sunday’s season opener mentioned, it was even worse than that when it got here to defending QB Jordan Love. The official stats mentioned the Vikings hit Love 15 occasions. OC Adam Stenavich mentioned it was 18. Either quantity is means too excessive for the Packers’ liking. Stenavich mentioned he is “not going to freak out or overreact or anything like that.” Love mentioned he is “always going to have confidence in those guys that, hey, we’ll clean this stuff up.” But if the Packers do not repair their go safety, Love may not final lengthy. — Rob Demovsky

What we’re listening to on the Jets: QB Geno Smith is 4-0 with six TD passes and solely two interceptions in opposition to Jonathan Gannon-coached defenses (when he confronted the Cardinals because the Seahawks’ QB). Smith is not placing any inventory in these numbers, saying, “Nothing in the past really matters.” Smith’s confidence is excessive after an environment friendly opener — no turnovers, no sacks and the second-lowest off-target fee (4.3%) within the league. — Rich Cimini

Stat to know: Dating again to Week 15 of final season, the Packers have a minus-69 level differential within the fourth quarter. That’s essentially the most within the NFL over that span and led to 6 straight losses. — ESPN Research

Bold prediction: The Jets will report an interception. It’s lastly going to occur! As effectively as Week 1 went for the Jets, they didn’t report a choose — as they did in each sport final season. The streak (curse?) ends Sunday … even in a loss. — Walder

Viewers ranking (out of 10): 7.2. Sneaky watchable sport in New York, the place the Jets look mighty competent, and the Packers are reeling after their late-game collapse in opposition to the Vikings. Something thrilling to observe: In a one-week pattern, it appears to be like just like the Packers have accelerated their tempo of play and uncorked Love accordingly. More snaps! More throws! More pleasure! — Solak

Injuries: Packers | Jets

Fantasy nugget: Love threw for 387 yards — the second-most of his profession — in Week 1 and tried 42 passes. Green Bay struggled to run the ball with out RB Josh Jacobs (commissioner exempt list), and its offensive line ranked twenty fifth in run block win fee (71.5%). The Packers can be smart to proceed leaning on the passing sport, benefiting Love, Christian Watson and Matthew Golden. See Week 2 rankings. — Moody

Betting perception: Love is 0-8 ATS in his profession as a highway favourite of at the very least three factors — however this matchup offers him an opportunity to interrupt it. He threw for 2 touchdowns, and the Jets’ secondary confronted little resistance from Tennessee. If Green Bay can get extra touchdowns, it may possibly cowl. Read more. — Maldonado

Maldonado’s choose: Packers 27, Jets 17
Moody’s choose: Packers 27, Jets 23
Walder’s choose: Packers 24, Jets 16
FPI prediction: GB, 62.6% (by a median of three.2 factors)

Matchup must-reads: Packers’ No. 1 task after loss: Protect Love … Why the Jets feel their TE room ‘is a weapon’ for them … Jets make moves to address depth with Cooper, Fitzpatrick hurt

1 p.m. ET | Fox | PHI -7 (39.5 O/U)

What we’re listening to on the Eagles: Philadelphia generated 18 pressures in Week 1, the third most within the NFL. That could possibly be an issue if it continues for QB Cam Ward, who was 5-of-11 for 33 yards when pressured by the Jets within the opener. Philadelphia sacked the elusive QB Jayden Daniels solely as soon as final week, nevertheless, DT Jalen Carter got here out of that sport with a wrist injury. DC Vic Fangio is searching for an excellent higher effort in opposition to Tennessee. “I thought our pass rush overall, when our guys that mainly rushed the passer, was inconsistent and really wasn’t good enough,” he mentioned. — Tim McManus

What we’re listening to on the Titans: The Titans struggled to cease the run final week, permitting the Jets to hurry for 152 yards. They had been with out final season’s main tackler Cedric Gray, however he’ll probably go concussion protocol and return to play in opposition to the Eagles. RB Saquon Barkley presents an excellent greater problem. “He’s really good,” DC Gus Bradley mentioned. “He will run through darkness, and if he can hit it with a full head of steam, he’s really difficult. We’ve got to set the edge, make him stop his feet a little bit.” — Turron Davenport

Stat to know: The Titans had 195 whole yards in Week 1, that includes zero offensive performs longer than 14 yards. That marked their first sport with no 15-yard performs since Week 17 of 2008. — ESPN Research

Bold prediction: Ward will throw at the very least three interceptions. Ward is coming off a tough begin to the season, because the Titans ranked third in go fee over anticipated, per NFL Next Gen Stats. Tennessee can be prone to be trailing on this sport, and the Eagles definitely have the defensive expertise to take the ball away. That’s a number of alternative to make errors. — Walder

Viewers ranking (out of 10): 5.4. The Titans are a brutal watch — riddled with execution errors — and the Eagles are nonetheless determining their new offense below Sean Mannion. I count on a run-heavy method as Philadelphia leans on its elite protection to win a low-scoring sleeper. — Solak

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‘You have been terrible’: Stephen A. unloads on Watson’s latest feedback

Injuries: Eagles | Titans

Fantasy nugget: Eagles WR DeVonta Smith‘s six targets and eight.3 fantasy factors final week had been disappointing, particularly with A.J. Brown now in New England. QB Jalen Hurts unfold the ball round in Week 1, however Smith now faces a Titans protection that allowed 367 whole yards to the Jets. Garrett Wilson scored 13.9 fantasy factors in opposition to Tennessee, and I count on Smith to prime that. See Week 2 rankings. — Moody

Betting perception: The Eagles are 12-5 ATS on the highway because the begin of 2024, and this matchup performs to Philadelphia’s strengths. Tennessee managed 195 yards in opposition to the Jets, and Ward took three sacks behind a shaky line. The Eagles can strain him with out asking the offense to hold the sport, whereas Barkley and Hurts assault the protection. Read more. — Maldonado

Maldonado’s choose: Eagles 34, Titans 10
Moody’s choose: Eagles 31, Titans 16
Walder’s choose: Eagles 34, Titans 13
FPI prediction: PHI, 69.7% (by a median of 5.5 factors)

Matchup must-read: Eagles placing LG Dickerson (knee) on injured reserve

1 p.m. ET | Fox | CAR -2.5 (43.5 O/U)

What we’re listening to on the Panthers: Coach Dave Canales admitted Wednesday that opposing defenses know that the Carolina passing sport is constructed round WR Tetairoa McMillan. But that information has some benefits, because it results in optimistic attracts for different targets to get open. Case in level: Jalen Coker‘s 138-yard, two-touchdown efficiency in Week 1. Canales mentioned much-maligned 2024 first-round choose Xavier Legette, who was held with no catch in opposition to Chicago, ought to see “great” matchups all through the season, maybe as early as Sunday. — Mike Kaye

What we’re listening to on the Falcons: RB Bijan Robinson is not simply the Falcons’ main playmaker on the bottom. He is likely to be the group’s major menace within the passing sport as effectively, because the QB state of affairs stays in flux. Robinson had the NFL’s highest goal share fee (47.6%) final week, along with a career-high 65.9% contact fee. He additionally had a career-high 114 yards after the catch, the second-highest whole by a working again in a sport since 2024. — Marc Raimondi

Stat to know: Panthers QB Bryce Young is 0-7 in his profession in Weeks 1-2. Josh McCown (0-10) is the one QB since 1970 with an extended profession dropping streak than Young in Weeks 1-2. — ESPN Research

Bold prediction: Panthers RB Chuba Hubbard will probably be held to below 3.5 yards per carry. The Falcons allowed simply 0.7 yards earlier than contact per rush in Week 1 (second greatest). And if the Panthers take the lead, then the Falcons ought to know that there are many runs coming. — Walder

Viewers ranking (out of 10): 5.9. The Panthers and Falcons gave us an awesome overtime game final season. (Young threw for 448 yards!) But that is the type of contest for which you tune in throughout the second half as NFL RedZone alerts you that it is a enjoyable one. If QB Jack Strand makes his first profession begin in Atlanta, it will get a “morbid curiosity” enhance. — Solak

Injuries: Panthers | Falcons

Fantasy nugget: Opposite of Walder’s prediction, I believe Hubbard will do effectively this week. He scored 23.7 fantasy factors on 13 touches in Week 1, whereas Jonathon Brooks managed simply 7.2 factors on 5 touches. Carolina seems to be easing Brooks again into motion, leaving Hubbard with the bigger function. The Panthers led the NFL in run block win fee (82.7%) final week and face a Falcons protection lacking defensive deal with Da’Shawn Hand (quadriceps). See Week 2 rankings. — Moody

Betting perception: Unders are 17-8 up to now 25 conferences between the Panthers and Falcons. That can proceed as a result of each offenses have causes to play conservatively. Atlanta can lean closely on Robinson in opposition to a Carolina protection that simply allowed 291 speeding yards, shortening the sport. Meanwhile, Carolina’s turnover considerations on offense are nonetheless there. Sustained speeding drives and fewer possessions favor one other lower-scoring assembly. Read more. — Maldonado

Maldonado’s choose: Panthers 20, Falcons 17
Moody’s choose: Panthers 23, Falcons 16
Walder’s choose: Panthers 26, Falcons 13
FPI prediction: ATL, 57.6% (by a median of 1.8 factors)

Matchup must-reads: Young’s 4-1 record vs. Falcons a harbinger for Week 2? … Falcons’ Penix ‘close’ to return, still mum on Week 2 … Canales: Panthers need to ‘play way better football’ … Falcons QB unclear with injured Rush, Tagovailoa

1 p.m. ET | CBS | TB -8.5 (41.5 O/U)

What we’re listening to on the Browns: While a lot of the main focus is on the Browns’ struggling offense, Cleveland’s protection additionally had a disappointing displaying in Week 1, permitting 34 factors in its first sport below DC Mike Rutenberg. The Browns performed extra zone protection than in previous seasons — their fifth-highest fee since 2023 — however coaches and defenders insist the change is not the explanation for his or her points. “It’s definitely just playing 11 as 1. The scheme is set perfectly,” DE Jared Verse mentioned. — Daniel Oyefusi

What we’re listening to on the Buccaneers: Bucs senior offensive assistant/go sport specialist Ken Zampese, who was the Browns’ QBs coach in 2018, informed me of QB Baker Mayfield and the Browns: “They had the guy. They had the guy and they gave him up. … The script got flipped and the city came alive because they finally drafted a quarterback that worked out for them and they mucked it up.” This is not the primary time Mayfield has confronted his former group since his departure in July 2022 — he did so with the Panthers in September 2022 — but it surely does mark the primary time the man on the opposite facet of the sector is the one who changed him in Deshaun Watson. — Jenna Laine

Stat to know: Cleveland generated 4 pressures in Week 1, the fewest within the NFL, after having the fourth-highest strain fee final season (36%). Verse, acquired within the Myles Garrett trade, didn’t have a QB strain in Jacksonville. — ESPN Research

Bold prediction: Browns backup QB Shedeur Sanders will throw a landing go on this sport. The Browns will lastly come to their senses earlier than the top of this sport and can bench Watson. At that time will probably be too late for Cleveland to win, however Sanders will at the very least handle a garbage-time rating. — Walder

Viewers ranking (out of 10): 4.3. I do not actually need to watch the Browns, and the Buccaneers aren’t sufficient to maneuver me off my spot. I count on most Cleveland video games to play out because the Jaguars sport in Week 1 did — large first-half lead, largely meaningless second half — and people video games turn into much more uninteresting once they repeat. — Solak

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Chiefs get optimistic information on CB Mansoor Delane

Injuries: Browns | Buccaneers

Fantasy nugget: Cleveland allowed Jaguars QB Trevor Lawrence to attain 26.1 fantasy factors final week. Mayfield has averaged 18.4 fantasy factors per sport since becoming a member of Tampa Bay, and its offensive line ought to give him time for WRs Emeka Egbuka and Chris Godwin Jr. to get open. See Week 2 rankings. — Moody

Betting perception: The Buccaneers are 1-6 ATS as residence favorites because the begin of final season, which might proceed as a result of they have not proven sufficient offensive explosiveness. Tampa Bay managed solely 282 yards in Week 1, whereas Cleveland’s 34-10 loss was uglier than Watson’s precise efficiency. If the Browns’ protection rebounds, Cleveland can maintain this sport comfortably contained in the quantity. Read more. — Maldonado

Maldonado’s choose: Buccaneers 17, Browns 10
Moody’s choose: Buccaneers 35, Browns 13
Walder’s choose: Buccaneers 27, Browns 7
FPI prediction: TB, 78.6% (by a median of 8.5 factors)

Matchup must-reads: Watson: Focus on winning, not job security … Bucs’ Zampese says Browns messed up by trading Mayfield … Browns place RB Sampson on IR with knee injury

4:05 p.m. ET | CBS | DEN -2.5 (45.5 O/U)

What we’re listening to on the Jaguars: The Broncos have somebody extra to fret about that they did not throughout final season’s matchup: Travis Hunter. Hunter did not play in December’s matchup due to his knee harm, however he is now the Jaguars’ prime nook and offers the offense one other playmaker. Hunter performed solely 4 offensive snaps within the opener in opposition to Cleveland, and coach Liam Coen mentioned Hunter’s function could possibly be a lot greater this week. “You want to continue to do what we think is going to give us the best chance at winning throughout the course of the week,” he mentioned. “And if that’s Travis getting more touches, then absolutely will [get him more touches].” — Mike DiRocco

What we’re listening to on the Broncos: It’s a query of whether or not the Broncos persist with their phrase on offense in opposition to the one group that beat them at residence within the common season in 2025. All offseason, the Broncos mentioned they need and have to decide to a greater constructed run sport. Then that they had all of six carries within the first half of their Week 1 matchup. Coach Sean Payton admitted that quarterback Bo Nix‘s struggles might, partly, be positioned on the truth that “our run-pass ratio was skewed and off.” — Jeff Legwold

Stat to know: The Jaguars have scored at least 23 points in 12 straight games, including the playoffs. That’s the longest active streak in the NFL and their longest in team history. They’re averaging 32.2 points per game in that stretch. — ESPN Research

Bold prediction: Nix will record a QBR of 65 or higher after a brutal Week 1 in which he posted an 8.3. Everything went wrong for Denver, and this is a little blind faith in an offensive rebound — even if I’m predicting it to come in a narrow loss. — Walder

Viewers ranking (out of 10): 8.8. The Jaguars and Broncos had an incredible contest final season, which the Jags gained. Denver, embarrassed by Kansas City and on a brief week, will come into this rematch with vengeance on its thoughts. But does OC Davis Webb have what it takes to settle Nix down in Week 2? Lots of narratives! — Solak

Injuries: Jaguars | Broncos

Fantasy nugget: Jaguars WR Parker Washington opened 2026 with a 28.6% goal share and 19.3 fantasy factors. He runs most of his routes from the slot, which ought to assist him keep away from Broncos CB Pat Surtain II on many snaps. Washington additionally scored a career-high 26.5 fantasy factors in opposition to Denver final season. See Week 2 rankings. — Moody

Betting perception: The Broncos are 3-9 ATS as favorites because the begin of final season (1-5 ATS of their previous six video games as favorites), placing the Jags in a great spot. Denver’s offense offers me pause, managing 176 yards and three.7 yards per play in Week 1, whereas Nix turned it over twice with 4 sacks. Now Jacksonville brings a go rush that produced 5 sacks in opposition to Cleveland. Read more. — Maldonado

Maldonado’s choose: Jaguars 24, Broncos 17
Moody’s choose: Broncos 27, Jaguars 24
Walder’s choose: Jaguars 27, Broncos 24
FPI prediction: JAX, 63.1% (by a median of three.6 factors)

Matchup must-reads: Is Lawrence’s hot start for the Jaguars sustainable? … Broncos face tough opening stretch, try to avoid slow start

4:05 p.m. ET | CBS | LAC -6.5 (43.5 O/U)

What we’re listening to on the Raiders: QB Kirk Cousins performed effectively in his debut, however his limitations as a passer had been evident. Against the Dolphins, he accomplished 1 of seven go makes an attempt for 21 yards and two interceptions on throws for 10-plus air yards. The Raiders usually are not anticipating Cousins, 38, to create a ton of explosive performs within the passing sport. The blueprint for the Raiders’ success offensively will probably be controlling the time of possession via brief and occasional intermediate throws and a powerful speeding assault. — Ryan McFadden

What we’re listening to on the Chargers: The Chargers’ offense got here to a screeching halt in final week’s loss after WR Ladd McConkey left with a rib injury. McConkey’s standing for Sunday stays up within the air, but when Week 1 is any indication, this offense wants him to thrive. “We’re hoping for the best for Ladd, and whatever the case may be, the guys behind him will step up and make some plays,” QB Justin Herbert mentioned. — Kris Rhim

Stat to know: RB Ashton Jeanty might be part of Marcus Allen (1986) as the one gamers in Raiders historical past to begin a season with two video games of 100-plus speeding yards. — ESPN Research

Bold prediction: The Raiders won’t sack Herbert. Maxx Crosby is a harmful go rusher, definitely, however with Joe Alt and Rashawn Slater at deal with, the Chargers are effectively outfitted to deal with him. — Walder

Viewers ranking (out of 10): 6.7. The Chargers’ face-plant against the Cardinals will not be quickly forgotten, however the alarm bells may be silenced with a convincing win over the Raiders. Jeanty bought utilization corresponding to Bijan Robinson/Jahmyr Gibbs in Week 1 and is rapidly rising up the appointment viewing ranks. — Solak

Injuries: Raiders | Chargers

Fantasy nugget: Herbert was pressured on 16 of 39 dropbacks in Week 1, and the Chargers ranked twenty seventh in go block win fee (39.3%). The Raiders sacked Dolphins QB Malik Willis 5 occasions final week. McConkey’s standing can be important to Herbert’s success. He averaged 10.3 yards per try with McConkey on the sector, in contrast with 5.4 after McConkey left. See Week 2 rankings. — Moody

Betting perception: The Chargers are 11-1 ATS in division video games below coach Jim Harbaugh. The Raiders look higher outfitted to maintain this contained in the quantity as a result of they protected Cousins with out permitting a sack and gave Jeanty 29 touches in Week 1. The Chargers allowed Arizona to manage possession for 37 minutes. That formulation can shorten this sport and make 6.5 factors useful. Read more. — Maldonado

Maldonado’s choose: Chargers 21, Raiders 20
Moody’s choose: Chargers 24, Raiders 20
Walder’s choose: Chargers 31, Raiders 20
FPI prediction: LAC, 70.2% (by a median of 5.6 factors)

Matchup must-reads: Raiders call TE Bowers day-to-day … Chargers WR McConkey day-to-day with rib injury

4:25 p.m. ET | Fox | DAL -4.5 (50.5 O/U)

What we’re listening to on the Commanders: In the opener, Washington allowed 4 performs of 30 yards or extra, accounting for 180 of Philadelphia’s 318 yards. In two video games versus Dallas a season in the past, Washington allowed 4 go performs of 30 yards or longer and two touchdowns — and Cowboy WRs CeeDee Lamb and George Pickens are big-play targets. Another issue: Lamb is 6-foot-2 and Pickens is 6-3 — going through two corners listed at 5-10 (Mike Sainristil) and 5-9 (Amik Robertson). But DC Daronte Jones identified, “They’ve dominated DBs in this league regardless of size.” — John Keim

What we’re listening to on the Cowboys: The Cowboys haven’t began 0-2 since 2010, which ultimately led to the primary and solely in-season teaching change Jerry Jones has ever made. Since 1989, when Jones took over, the Cowboys have opened the season with a loss 13 occasions and responded with a win in Week 2. Eight of these occasions they ended up making the playoffs. It may not be must-win, however they can not let the early season get away from them. “I wouldn’t say so critical to where people are on their tippy toes, but definitely urgent because division games such as the Giants was too,” Pickens mentioned. — Todd Archer

Stat to know: Since division realignment in 2002, 11 groups have began 0-2 with each losses in divisional video games. The 2025 Bears are the one a kind of groups to make the playoffs. — ESPN Research

Bold prediction: There will probably be 60 or extra factors scored on this sport. Even in a loss, Dak Prescott recorded an 89 QBR final week in opposition to the Giants — and the Commanders’ go rush is definitely much less menacing than New York’s. And whereas the Cowboys may determine their protection sooner or later this season, I doubt that change will occur so quickly after a tough opening sport. — Walder

Viewers ranking (out of 10): 7.1. Two 0-1 groups, each with a divisional loss, going through 0-2 … that is very excessive stakes. The watchability is harm right here by Dallas’ protection, which was riddled with simple errors in Week 1 — laborious to observe. Washington’s protection? Surprisingly plucky. This will probably be an in depth one. — Solak

Injuries: Commanders | Cowboys

Fantasy nugget: RB Jacory Croskey-Merritt led Washington’s backfield with 16 carries in Week 1, in contrast with seven for Rachaad White and 4 for Kaytron Allen. He now faces a Cowboys protection that surrendered 165 speeding yards to the Giants. Croskey-Merritt additionally scored 22.5 fantasy factors in opposition to Dallas in Week 17 final season. He has an opportunity to ship RB2 manufacturing this week. See Week 2 rankings. — Moody

Betting perception: The Cowboys are 2-9 ATS as favorites below coach Brian Schottenheimer. The Cowboys simply allowed the Giants 394 yards, together with 165 on the bottom, and touchdowns on all 4 pink zone journeys. Washington sustained drives in opposition to a a lot more durable Eagles protection. If QB Jayden Daniels does that once more, Dallas could have hassle overlaying 4.5. Read more. — Maldonado

Maldonado’s choose: Commanders 27, Cowboys 24
Moody’s choose: Cowboys 38, Commanders 24
Walder’s choose: Cowboys 34, Commanders 27
FPI prediction: DAL, 64.1% (by a median of 4.1 factors)

Matchup must-read: Cowboys’ TD record: I caught a TD pass from Prescott

4:25 p.m. ET | Fox | SEA -3.5 (41.5 O/U)

What we’re listening to on the Seahawks: Every NFL group says it has religion in its backup QB as soon as he is pressed into motion. That’s true with Seattle and Drew Lock, who will begin Sunday and maybe past as Sam Darnold offers with a glute injury. But the Seahawks have been saying that about their QB2 for some time. Lock’s final begin for the group was in 2023, when he beat the Eagles in primetime. “We believe that he’s the best second-string quarterback in the league,” DT Leonard Williams mentioned Wednesday. “… I remember that Eagles game a few years back where he stepped up and won us the game. He’s done it and shown it multiple times now. That has instilled a lot of trust in his teammates and his team.” — Brady Henderson

What we’re listening to on the Cardinals: The Cardinals are aware of how gifted the Seahawks’ protection is — particularly coach Mike LaFleur, who performed Seattle 3 times final season with the Rams, together with within the NFC Championship Game. He referred to as Seattle’s protection final season not simply “the best defense in football” however “one of the best defenses probably this league has ever seen last year.” This season, LaFleur mentioned Seattle would not have any weaknesses on protection. On the flip facet, QB Jacoby Brissett mentioned Arizona’s offense, which put up 26 factors in a Week 1 win, did simply sufficient to win the sport. — Josh Weinfuss

Stat to know: Cardinals TE Trey McBride has averaged 95.4 receiving yards in 5 video games in opposition to Mike Macdonald defenses. That’s the third most by any participant versus Macdonald (minimal of three video games, together with the playoffs). — ESPN Research

Bold prediction: Seahawks rookie RB Jadarian Price will report 100 whole yards. I think about the Seahawks will need to depend on the bottom sport and protection with Lock beginning instead of Darnold. Price appeared good in Week 1, so even when he is nonetheless sharing the RB workload with George Holani, he might have an enormous sport. — Walder

Viewers ranking (out of 10): 6.3. This can be a enjoyable primetime watch: What can Lock do? Are the Cardinals legit or was Week 1 a blip? But on a busy NFL Sunday, it simply would not have sufficient draw. If the Cardinals’ offense can produce in opposition to a Macdonald protection, I’ll bump them up the scores subsequent week. — Solak

Injuries: Seahawks | Cardinals

Fantasy nugget: Price averaged 5.2 yards per carry in his NFL debut, gaining 52 yards on 10 makes an attempt whereas including two receptions. He performed fewer than half of Seattle’s offensive snaps, leaving room for an even bigger workload. With Darnold out and the offensive line ranked seventh in run block win fee (78.5%), Price might see considerably extra touches in Week 2. See Week 2 rankings. — Moody

Betting perception: Since 2016, groups that gained in Week 1 as at the very least 7-point underdogs are 6-1-1 ATS in Week 2 (Cardinals). Arizona’s Week 1 upset appeared earned. It outgained the Chargers whereas Brissett threw for 277 yards with no turnover. Seattle wanted three interceptions to defeat New England 13-10 and went 2-for-11 on third down. Arizona can maintain this inside a area objective. Read more. — Maldonado

Maldonado’s choose: Seahawks 20, Cardinals 19
Moody’s choose: Seahawks 24, Cardinals 23
Walder’s choose: Seahawks 23, Cardinals 13
FPI prediction: ARI, 54.8% (by a median of 1.2 factors)

Matchup must-reads: Seahawks confident in QB Lock … Cardinals pull off Week 1’s biggest upset

4:25 p.m. ET | Fox | SF -13.5 (44.5 O/U)

What we’re listening to on the Dolphins: QB Malik Willis registered one of many longest occasions to throw averages within the NFL final week, however that is a by-product of his type of play. Willis mentioned the idea of an “internal clock” is “made up,” and mentioned it is his duty every play to really feel when the frenzy is coming. OC Bobby Slowik mentioned it is a work in progress between himself and Willis, discovering a steadiness between getting the ball out rapidly in sure conditions and permitting Willis to execute his distinctive capacity to maintain performs alive. In both situation, Slowik mentioned he isn’t wanting to remove what Willis does greatest. — Marcel Louis-Jacques

What we’re listening to on the 49ers: The 49ers are massive favorites, however to win it, they’re going to have to beat the Dolphins and any remaining fatigue from their weeklong journey to Australia. LB Fred Warner mentioned coach Kyle Shanahan has labored laborious to verify the Niners do not have a letdown after such an emotional win final week, but it surely’s nonetheless truthful to marvel if there will probably be any lingering results. “[Coach Shanahan] paints the picture perfectly for the situation week to week, and he did that exact same thing this week, letting us know the challenge that the Dolphins present and then the challenge that we have as a team to really get better coming off of the Rams game.” — Nick Wagoner

Stat to know: Dolphins RB De’Von Achane had 36 speeding yards in opposition to the Raiders in Week 1. Last season, he did not have back-to-back video games with fewer than 50 speeding yards. — ESPN Research

Bold prediction: The Dolphins will not report a single QB hit in opposition to Brock Purdy. The 49ers did not enable the Rams to sack Purdy in any respect in Week 1. That means the Dolphins’ go rush, which made the Raiders’ offensive line look nice final week, ought to be a chunk of cake. — Walder

Viewers ranking (out of 10): 4.6. The greatest unfold of the week comes with out a lot intrigue save for circadian rhythm watchers, who may count on a flat 49ers sport in Week 2 because the group returns from Australia. The Dolphins’ offense was not as enjoyable as I hoped it is likely to be with Willis and Achane within the backfield. — Solak

Injuries: Dolphins | 49ers

Fantasy nugget: Purdy put up 21.1 fantasy factors in Week 1 regardless of a tricky matchup. Now he will get a Dolphins protection that allowed Raiders QB Kirk Cousins to throw for 160 yards and three touchdowns final week. With WR Mike Evans, RB Christian McCaffrey and TE George Kittle round him, I count on one other massive sport from Purdy. See Week 2 rankings. — Moody

Betting perception: The 49ers have coated 4 straight video games as double-digit favorites, and Miami suits the profile for an additional. The Dolphins managed simply 13 first downs and allowed 5 sacks in Week 1. San Francisco rushed for 174 yards, transformed 7 of 12 third downs and may pressure Willis into one other unfavorable, pass-heavy sport script. Read more. — Maldonado

Maldonado’s choose: 49ers 34, Dolphins 7
Moody’s choose: 49ers 30, Dolphins 10
Walder’s choose: 49ers 34, Dolphins 14
FPI prediction: SF, 92.1% (by a median of 14.5 factors)

Matchup must-reads: QB Willis takes blame for five-sack debut … Stribling to miss 10 weeks; Tonges out for season … 49ers find needed balance in run game with McCaffrey, Black

8:20 p.m. ET | NBC | KC -6.5 (46.5 O/U)

What we’re listening to on the Colts: Indianapolis conceded a mistake and made a important change in defensive signal-callers this week, transferring from security Cam Bynum to LB Akeem Davis-Gaither. The unique plan for Bynum to put on the coach-to-defense helmet transmitter turned disastrous in Week 1 when he was unable to simply navigate between his deep protection function, huddling the protection and making calls. That led to quite a few situations of the protection being out of place earlier than performs if it was even lined up in any respect. The change was essential as a result of the Colts had been cautious that QB Patrick Mahomes and the Chiefs would take benefit. — Stephen Holder

What we’re listening to on the Chiefs: Despite scoring 31 factors of their Week 1 win, the Chiefs nonetheless lacked constant manufacturing from their receivers. In reality, the Chiefs’ prime trio of WRs — Rashee Rice, Xavier Worthy and Tyquan Thornton — mixed to generate six receptions on 9 targets for simply 37 yards. But OC Eric Bieniemy continues to be assured. “Our guys are working,” Bieniemy mentioned. “Yes, I want everybody to come out there and be an All-Pro on every single weekend. … They know that at some point in time, their numbers will show up. We’re not worried about that.” — Nate Taylor

Stat to know: Kenneth Walker III had two rushes of 20-plus yards in Week 1, which is already greater than all of Kansas City’s RBs in 2025. — ESPN Research

Bold prediction: Mahomes will full 12 passes to gamers aligned within the slot, one thing the Chiefs achieved solely as soon as final season. I’m a reasonably large believer in Colts CBs Sauce Gardner and Charvarius Ward. So in the event that they maintain the surface receivers, Mahomes might look inside, be it to Travis Kelce, Rice or another person. — Walder

Viewers ranking (out of 10): 7.3. I had the Chiefs ranked fairly low in my preseason watchability rankings — then that they had their greatest day working the soccer in over 5 seasons on Monday night time. Stock up! The Colts’ protection is near-unwatchable ranges of dangerous proper now, so this sport may find yourself wanting just like the 2024 Chiefs: lengthy, sluggish drives to guard a one-score lead. — Solak

Injuries: Colts | Chiefs

Fantasy nugget: The Chiefs talked all offseason about working the ball extra, and so they backed it up in Week 1. Walker completed with 23 carries and 34.1 fantasy factors. Now he faces a Colts protection that allowed the Ravens’ Derrick Henry to attain 35.3 fantasy factors final week. Kansas City ought to proceed leaning on Walker, placing him in an awesome spot for an additional massive sport. See Week 2 rankings. — Moody

Betting perception: Chiefs unders are 35-17 up to now 4 seasons, the NFL’s highest below fee. The improved run sport might push these video games over with Walker, whereas Indianapolis allowed Baltimore to common 7.9 yards per play and rating 41 factors. The Colts can contribute with RB Jonathan Taylor, however their protection creates the circumstances for a higher-scoring sport. Read more. — Maldonado

Maldonado’s choose: Chiefs 31, Colts 24
Moody’s choose: Chiefs 30, Colts 23
Walder’s choose: Chiefs 20, Colts 17
FPI prediction: KC, 75.5% (by a median of seven.5 factors)

Matchup must-reads: Colts’ D looked lost vs. Ravens, and Mahomes is next … Chiefs expecting rookie CB Delane to play

Monday, 8:15 p.m. ET | ESPN | LAR -7 (48.5 O/U)

What we’re listening to on the Giants: New York feels good after Week 1. The Giants had been the bodily, run-first group they informed everybody they needed to turn into. Step one, achieved. The subsequent step is on the highway in opposition to the Rams. “It’s going to be a great test,” QB Jaxson Dart mentioned. Coach John Harbaugh mentioned he would not assume there’s any means his group has a letdown. The gamers know it is simply one in all 17 video games and this group nonetheless has a lot to show. — Jordan Raanan

What we’re listening to on the Rams: If DT Aaron Donald performs Monday night time, it should have been 981 days since his final NFL sport. Donald, who got here out of retirement in late August, didn’t journey to Melbourne, Australia, for Week 1. But when Donald does return, coach Sean McVay says he would not count on to see a drop-off from how Donald was enjoying when he initially retired in March 2024. When requested whether or not he expects to see Donald play on the identical stage, he mentioned: “I do. That’s what my expectations are and my level of confidence in him.” — Sarah Barshop

Stat to know: After scoring a mixed 12 factors in Week 1 from 2023 to 2025, the Giants scored 28 factors in opposition to the Cowboys. They averaged an NFL-high 9.7 performs per drive. — ESPN Research

Bold prediction: Rams TE Colby Parkinson will catch a landing go. He had just one reception in Week 1, however he ran a route on 52% of Los Angeles’ dropbacks — placing him forward of second-year TE Terrance Ferguson. — Walder

Viewers ranking (out of 10): 7.8. This sport is abruptly excessive stakes for the 0-1 Rams going through a 1-0 Giants group that has a brand new id and tons of momentum. High on my listing for Week 2 is evaluating Dart in opposition to a greater protection than Dallas. Important sport! — Solak

Injuries: Giants | Rams

Fantasy nugget: RB Cam Skattebo dealt with 60% of the Giants’ backfield touches in Week 1, together with 4 pink zone carries. New York ranked eighth in run block win fee (78.4%), whereas Los Angeles allowed 174 speeding yards in Week 1. The Rams’ Myles Garrett (knee) is sidelined, and Donald hasn’t performed in over two seasons and could possibly be restricted if he returns. Skattebo has a positive matchup and a considerable workload. See Week 2 rankings. — Moody

Betting perception: Dart is 6-2 ATS in his profession as an underdog of at the very least three factors. His mobility and the Giants’ speeding offense (165 yards in Week 1) give New York a path, whereas the Rams gave up 5.8 yards per carry. Without Garrett, L.A. offers Dart extra freedom to increase performs and stress the protection together with his legs. Read more. — Maldonado

Maldonado’s choose: Rams 28, Giants 24
Moody’s choose: Rams 33, Giants 24
Walder’s choose: Rams 30, Giants 20
FPI prediction: LAR, 67.9% (by a median of 4.6 factors)

Matchup must-reads: Giants’ Harbaugh admits tackling Nabers to relax WR’s injury fears … Best and worst NFL teams’ travel: Rams, 49ers, Steelers divulge it all