Yankees vs. Rays odds, prediction, line, time: 2026 MLB picks for May 22 from proven model in Gerrit Cole’s return

Gerrit Cole will make his 2026 season debut when the New York Yankees battle the American League East Division-rival Tampa Bay Rays on Friday evening. The former Cy Young Award winner is returning after having Tommy John surgical procedure and New York is hoping to restrict him to round 85 to 90 pitches. The Rays (33-15), who lead the AL East and have received 4 video games in a row, are 14-10 on the highway this season. The Yankees (30-21), who’re second in the division, are 16-8 on their residence subject in 2026.

First pitch from Yankee Stadium is about for 7:05 pm ET. New York is a -147 favourite on the cash line (danger $147 to win $100) in the most recent Yankees vs. Rays odds, whereas the over/underneath, is 7.5. Before making any Rays vs. Yankees picks, make sure to see the Rays vs. Yankees predictions and betting advice from SportsLine’s proven computer model.

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The SportsLine Projection Model simulates each MLB sport 10,000 occasions, and enters Week 9 of the MLB season on a red-hot 12-1 run on all top-rated MLB picks. It additionally excelled at making residence run prop picks in 2025, returning almost 30 models of revenue. Anyone following its MLB betting picks at sportsbooks and on betting sites might have seen sturdy returns.

Now, the model has set its sights on (*22*) and simply locked in its picks and MLB predictions. You can head to SportsLine now to see the model’s picks. Here are a number of MLB odds and betting traces for Yankees vs. Rays:

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Top Rays vs. Yankees predictions

After 10,000 simulations of Rays vs. Yankees, the model is going Over 7.5 mixed runs. For over/under bettingthe Over has hit in seven of the previous 10 head-to-head conferences with one push. The Over has additionally hit in seven of the final 9 Tampa Bay video games, and in 4 of the final six New York video games. The Over has hit in eight of the previous 15 New York video games when the road is between 8 and eight.5 at video games performed at Yankee Stadium.

SportsLine’s model initiatives 1.5 complete bases or extra for the Rays’ Chandler Simpson, Junior Caminero, Jonathan Aranda and Yandy Diaz. The Yankees, in the meantime, are projected to recover from 1.5 complete bases or extra from Ben RiceAaron Judge, Cody Bellinger, Jazz Chisholm and Paul Goldschmidt. Cole is projected to enter the sixth inning and strike out 5.3 whereas giving up 2.5 earned runs in his return. The model initiatives 10.2 mixed runs because the Over hits in 64% of simulations. Get the Rays vs. Yankees money-line pick at SportsLine.

How to make Yankees vs. Rays picks

After simulating each pitch of Yankees vs. Rays 10,000 occasions, the model additionally says one aspect of the cash line has all the worth. You can get that pick at SportsLine.

So who wins Rays vs. Yankees, and which aspect of the cash line has all the worth? Visit SportsLine now to see which side you need to jump on, all from the model that you have crushed your MLB picksand discover out.